RENEWAL OF THE COMMITTEES OF THE LATIN AMERICAN SOCIETY FOR IMMUNODEFICIENCIES 2020 As the requirement of LASID bylaws that states: “The minimum number of accredited members in good standing that
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Learn moreAbstract Background A post hoc analysis of two randomized, placebo–controlled, Phase 3 trials of intravenous reslizumab, an anti-interleukin-5 (IL-5) biologic for severe eosinophilic asthma. Methods Relationships between baseline blood...
Learn moreAbstract Background Improved survival in ADA-SCID patients is revealing new aspects of the systemic disorder. Although increasing numbers of reports describe the systemic manifestations of adenosine deaminase deficiency, currently there are...
Learn moreAbstract Background Previous proof-of-concept studies have shown that a short course of omalizumab can safely accelerate the oral immunotherapy schedule for multiple allergens simultaneously. Considering the high cost of medication, the...
Learn moreAbstract Studies of genetic blood disorders have advanced our understanding of the intrinsic regulation of hematopoiesis. However, such genetic studies have only yielded limited insights into how interactions between hematopoietic cells and...
Learn moreAbstract Background This paper presents a peculiar first case of an allergy to Silybum marianum (milk thistle) and Eragrostis tef (teff). Both teff and milk thistle have been presented in the literature (both domestic and foreign) in a...
Learn moreAbstract Purpose Patients with primary immunodeficiency disease (PID) have an increased risk of experiencing physical activity limitations, social difficulties, and psychological problems due to their chronic condition. Evaluation of their...
Learn moreAbstract Background Epinephrine auto-injectors are expected to deliver the drug intramuscularly. Objective To study whether injection through clothing influences the frequency of subcutaneous and intraosseous/periosteal deposition of...
Learn moreKey Points IRCTX muscle injury results in muscle fibrosis through macrophage-derived TGF-β1. FAPs respond to TGF-β1 by differentiating into fibroblasts. Conditional knockout and systemic inhibition of TGF-β1 attenuates IRCTX...
Learn moreKey Points NOD1 restricts replication of RNA viruses. The cumulative effects between NOD1 and MDA5 normal form are conserved. NOD1 degradation by the truncated form of MDA5 is specific to fish...
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